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Question: 20120071
Status
Final

References
Source 1:   2012 Heme & Lymph Manual & DB
pgs:  
Notes:  
Source 2:  
pgs:  
Notes:  


Question
Primary site--Heme & Lymphoid Neoplams: What is the primary site and how do I navigate the hemato manual to arrive at the answer? See discussion.

Discussion
2011 case: 15 cm mass involving terminal ileum, cecum and adjacent mesentery. Pathology diagnosed diffuse large b-cell lymphoma. Staging PET/CT revealed 2.5cm glucose avid mass at base of tongue and a left cervical lymph node. Biopsy of base of tongue: diffuse large B-cell lymphoma.

Answer
Go to database and look up 9680/3, which states that diffuse large B-cell lymphoma may have lesions in ileocecal region or jaws. Bone marrow and peripheral blood may be involved. Patients present with lymphadenopathy or mass lesions in extranodal site. Use Module 7 for assigning primary site. Since you have two extranodal sites and involvement of regional lymph nodes for one of those sites, use Rule PH36 and assign primary site C779.

History


Last Updated
08/29/2012

Date Finalized
08/29/2012