SEER Inquiry System - View
Source 1: Heme & Lymph Neo Manual & DB
Multiple primaries--Heme & Lymphoid Neoplasms: I am confused about Chronic & Acute as it relates to Rules M8-13, and the Database that states particular histologies have Chronic, Accelerated & Blast phases but the histology doesn't change. Does this mean Rules M8-13 don't apply because there isn't a transformation / a change in histology? See discussion.
Please clarify by stepping through the Database & Manual Modules to determine number of primaries.
01/2008 Chronic myeloid leukemia, Chronic phase - CR after TX
03/2010 CML, Accelerated Phase - CR after TX
02/2012 CML, Blast Crisis
Assign 9863 for CML in 2008. The 2010 diagnosis is the same histology. Per the Hematopoietic database, chronic and accelerated phase are alternate names. This is the same primary per Rule M2.
Blast phase (crisis) is also an alternate name for CML, which makes the 2012 diagnosis the same primary per Rule M2.
As you noted, not all histologies have transformations. If a transformation is not listed, rules M8-M13 do not apply. For these types of cases, use M15 and use the multiple primaries calculator.