SEER*Stat Installation

The installation program(s) for SEER*Stat are provided below. All new software releases will be posted here and will include the version number in the filename. SEER*Stat's title bar includes the version number so that you can see if you are using the latest version.

The SEER*Stat software has an auto-update feature. The software can be configured to automatically upgrade with the SEER*Stat release or to delay the update for a couple weeks after the release. See Auto-updating in SEER*Stat for more information.

Current SEER*Stat users may sign up for e-mail updates to receive advanced notice of software releases.

Installation Files

In most cases to use SEER*Stat, you must have access to the SEER Research Data. The installation program provided here does not include or provide access to these data. If you have not done so already, please follow the steps to Access the SEER Research Data.

SEER*Stat Readme File

---------------
SEER*Stat 8.1.5
---------------

The SEER*Stat statistical software provides a convenient, intuitive
mechanism for the analysis of SEER and other cancer-related
databases.  It is a powerful PC tool to view individual cancer
records and to produce the statistics listed below.  These statistics
are useful when studying the impact of cancer on a population.

Frequency and Rate Statistics
  -  Frequencies
  -  Row and column percentages
  -  Crude (non-adjusted) rates with standard errors and
     confidence intervals
  -  Age-adjusted rates with standard errors and confidence
     intervals
  -  Incidence-based mortality rates
  -  Rate ratios for significance testing

Trends Over Time (based on frequencies and rates)
  -  Percent changes (PC)
  -  Annual percent changes (APC) with confidence intervals
  -  Comparison of APCs with zero
  -  Comparison of two APCs with one another

Survival Statistics
  -  Observed survival
  -  Net survival (absence of other causes of death)
       -  Relative survival
       -  Cause-specific survival
  -  Crude probability of death (presence of other causes of death)
       -  Using expected survival
       -  Using cause of death
  -  Option to adjust for heterogeneity in withdrawal when using
     expected survival
  -  Comparison of two survival curves (Z-statistic)
  -  Conditional survival - a survival rate conditioned on having
     survived x years (for example, a 10-year rate for individuals
     having already survived 5 years)
  -  Actuarial and Kaplan-Meier methods
  -  Period survival for all survival session methods

Limited-Duration Prevalence Statistics
  - Prevalence counts
  - Crude (non-adjusted) percents
  - Age-adjusted percents
  - Profile survival for limited-duration prevalence (future)

Multiple Primary - Standardized Incidence Ratio Statistics
  Comparison of cancer incidence in a defined cohort of persons
  previously diagnosed with cancer to cancer incidence in the general
  population.  In other words, The MP-SIR session allows you to
  define a cohort of people based on first cancer diagnosis
  (exposure) and to follow them through time to compare their
  subsequent cancer experience (observed events) to population based
  expected values.

Case Listings
  - The values stored in the database for individual records are
    presented in a table.
  - You choose the variables displayed and select the records to be
    included in the table.

--------
FEATURES
--------

  -  Easy to use interface
  -  Comprehensive help system
  -  Ability to select/exclude cases using multiple primary criteria
     (i.e., SEER*Stat realizes a person can have more than one tumor)
  -  Handles complex selection/subset statements with support for
     full Boolean logic
  -  Multi-dimensional matrices for reporting results
  -  Support for copying and pasting cancer records and statistics
     into spreadsheet or charting/graphing packages
  -  Ability to export records and statistics to a generic data file
     for input by other statistical systems such as SAS
  -  Print preview
  -  User Profiles for managing workflow

---------------------------
CLIENT-SERVER CONFIGURATION
---------------------------

With this configuration, all data are stored in a centralized
location at the SEER Program and calculations are performed on SEER's
dedicated hardware.  If you utilize this mechanism, you do not need
to maintain the SEER data on your local computer system.  Each time
you execute an analysis, the parameters of your request will be
transferred over the Internet from your computer to the SEER*Stat
server.  Once the calculations are complete, the results will be
transferred back to your computer.  A high speed Internet connection
is required for this configuration.

-------------------
SYSTEM REQUIREMENTS
-------------------

  -  Pentium-based PC
  -  32-bit or 64-bit Microsoft Windows Operating System
     (Windows 7, Vista, XP, 2000, NT, 98, 95, etc.)
  -  800 x 600 or greater monitor resolution
  -  Microsoft Internet Explorer 4.0+ for viewing help
  -  32 MBs application RAM
  -  Approximately 6 MBs disk space
  -  High speed Internet connection (not a dial-up modem based) if
     using the client-server configuration

------------
INSTALLATION
------------

To install from the SEER Research Data DVD:
  -  Insert the DVD into the drive
  -  From the Start menu, choose Run...; type 
     [dvd-drive]:\SEER_1973_2010_SEERSTAT\install\setup.exe
  -  Follow the instructions on your screen

To install using the installation program from the Internet:
  -  Download the installation program from
     http://seer.cancer.gov/seerstat/software
  -  Within Windows, double-click on the downloaded file
  -  Follow the instructions on your screen

Unless the data location is changed from the default with the File,
Preferences... dialog, the DVD must be located in the drive or you
must have an account within the client-server configuration to
execute SEER*Stat.

--------------------------------
LOCAL AREA NETWORK INSTALLATIONS
--------------------------------

A single copy of the SEER*Stat executable and data can be placed on a
network for multiple persons to utilize.  This configuration is
highly recommended because updates to SEER*Stat can be performed on
the single network installation instead of modifying each user's
desktop PC.

Copy the contents of the [dvd-drive]:\SEER_1973_2010_SEERSTAT\bin 
directory (seerstat.exe and seerstat.chm) from the DVD to a location 
on the network accessible by all users.  Suppose this location is 
called "\\fileserv1\SEERStat".  Then copy the 
[dvd-drive]:\SEER_1973_2010_SEERSTAT\data directory and all its 
sub-directories from the DVD to this location.  This will yield a 
directory on your network called "\\fileserv1\SEERStat\data".

On each user's desktop PC, create a Windows shortcut to
"\\fileserv1\SEERStat\seerstat.exe".  The first time each user
executes SEER*Stat, it will display the Data Locations and the 
default User-Defined Variables Location (UVL). The default Data 
location is "\\fileserv1\SEERStat\data".  The UVL varies by the
version of Microsoft Windows.

If a network installation is configured, use must be confined to
persons that have completed the SEER Research Data Agreement.  If
others wish to make use of the system, each must complete the SEER
Program's Research Data Agreement available on the SEER Web page
at the following address.

http://seer.cancer.gov/dataagreements/seer.pdf

-------------------------------
REMOVING PREVIOUS INSTALLATIONS
-------------------------------

Existing versions of SEER*Stat do not need to be removed from your
system prior to installing this newer version.

This version may NOT allow you to analyze data contained on CDs/DVDs
earlier than SEER*Stat 6.3.6.  If you need to analyze data from earlier
CDs/DVDs, you may not want to overwrite an earlier installation with this
version.

If you wish to completely remove an earlier version prior to
installing this current version, use the Add/Remove Programs icon in
the Windows Control Panel.

----------------
REVISION HISTORY
----------------
03/28/2014 - Version 8.1.5
1.  Survival: A few cosmetic changes were made to the Parameters tab.
2.  The Help system has been updated to include recent changes.

03/18/2014 - Version 8.1.4
1.  New Expected Survival Tables available with November 2013 submission.
    The new life tables have data through 2009, but the more significant
    change is the fact that they only have ages through 99.  This will
    result in the exclusion of all patients with an age of diagnosis
    of 100+.  The new tables are used as the default for November 2013
    data.
2.  Survival: A new checkbox was added to the Parameters tab to censor
    cases when attained age exceeds the maximum age in the expected
    rate table. A new default expected rate table with maximum
    age of 99 years was provided.  When using this table, cases with
    age at diagnosis of 100 or greater will be removed from analysis.
3.	MP-SIR: There was the potential to have cases in the Case Listing
    which had negative person time when an exit point was specified
    (early exit or exit at event in rate file, etc.).
    These people are now removed from those types of runs.
    Exclusion counts have been updated to account for these excluded
    individuals.
4.	MP-SIR Tables: If Attained Calendar Year was a table dimension and
    a latency period was specified, the count of the number of people
    could have been off.   This would also affect other statistics that
    use the number of people such as:  mean person years at risk,
    mean age at exposure, and mean date of exposure.
    The other information tallied in the table  (person time, observed,
    expected, etc.. ) was being calculated correctly.
5.  A warning message was added at the start of Profile|Preferences to
    indicate that data locations cannot be changed when a session is
    open.       

01/16/2014 - Version 8.1.3
1.  Left-Truncated Life Tables session is no longer a beta feature.
2.  Added ability to include Standard Populations in the output for a
    Rate session.
3.  Added functionality for Delay Adjusting when using certain databases
    in Rate or Frequency sessions.
4.  Merged variables can now be used in defining groupings for other
    merged variables.  Merged variables are also allowed in case listings
    generated by Survival, MP-SIR and Left-Truncated Life Tables sessions.
5.  Fixed bug in setting of page types for printing of Left-Truncated
    Life Tables matrix.
6.  Upgraded functions for estimating number of matrix pages for
    Survival and Left-Truncated Life Tables sessions.
7.  Survival: Added more case count exclusion criteria when the “All tumors
    matching selection criteria” multiple primary option is specified.
    Life Pages were updated to contain additional information in footnotes.

09/09/2013 - Version 8.1.2
1.  Changed the writing of file associations in the registry from
    the HKEY_LOCAL_MACHINE hive to the HKEY_CURRENT_USER hive to
    ensure that updates will be performed without Admin privileges.
2.  Fixed bug in MP-SIR case listing so that each patient would have
    a record with a reason for exit and person time.

08/26/2013 - Version 8.1.1
1.  Survival and Left-Truncated Life Tables case listings now support
    unlimited number of output fields.  A new dimension is added
    to the table tab for Case Listing Only variables.  The Parameters
    and Table tabs have been switched in the survival tab order.
2.  Survival - added person shading to case listing when the MP
    option "All Cases Matching Criteria" is selected.
3.  Survival - Removed case-sensitivity when validating the names of
    COD variables.
4.  Survival now disallows age standardizing when the age standardizing
    variable has only one grouping.
5.  Left-Truncated Life Tables beta release. Added stability criteria.
6.  Fixed bug that allowed duplicate variable names in the dialog for
    resolving invalid session variables on load or database change.
7.  Variable Find dialog now returns found value to the search dialog
    and selects it there.
8.  Upgraded client-server data encryption software to latest version.

04/12/2013 - Version 8.0.4
1.  Survival case listing new fields added, change in expected.  New fields
    are age and year of last interval for the patient.  The interval expected
    survival included in the matrix is directly from the expected survival
    table used.  Previously, it was adjusted based on interval length.  
    e.g. Twelfth root was taken for monthly survival.
2.  Survival - fixed bug that prevented new session from opening when
    pre-calculated duration variables are not available.  Only 
    applicable to those using 8.0.3 (not released on public ports).
3.  Allow case listing matrix with no records to be copied to the
    clipboard (field names only).

03/15/2013 - Version 8.0.3
1.  Survival calculation can now be based on pre-calculated survival
    duration variables or on dates (begin and end dates).  The Pre-calculated  
    survival duration option will be the default for SEER databases starting  
    with the November 2012 submission.  The pre-calculated survival variables 
    in the SEER data (Nov 2012+) have been calculated using complete dates
    rather than just month and year.
2.  Survival session - the Case Listing option has been removed from the 
    session dropdown menu and is now available on the Parameters tab along 
    with the other display options.
3.  New matrix menu option added to extract the source session as a
    text file without having to open it in the interface.
In-house beta version only:
4.  The matrix export utility was implemented for Left-Truncated Life
    Tables.
     
02/19/2013 - Version 8.0.2
1.  MP-SIR – there was a problem that occurred only when using early 
    criteria.  The problem was limited to the case listing and frequency 
    statistics and did not impact the standard SIR analyses.  Highlighting 
    in case listing and record counts when producing frequencies were affected.
2.  Survival session - sessions would not execute when relative conditional 
    survival statistics were requested and included in the cumulative summary 
    pages.
3.  Survival session – survival case listings sessions would not execute if the 
    new multiple primary selection option was set to “All Tumors Matching 
    Selection Criteria”.  This did not impact standard survival analyses.
4.  Limited-duration prevalence – sessions would not execute only when the 
    multiple primary selection option was set to “All Tumors Matching Selection 
    Criteria”, age-adjusted prevalence was being calculated, and the age 
    variable for the age-adjustment was “Age recode” (the version with 18 age 
    groups – with 0-4 year olds combined).
5.	Fixed bug that showed up when deleting invalid variables on database change.  
    SEER*Stat now preserves variables in the table dimension and retains their 
    order.
6.	Fixed bug to prevent updates to the current user profile while a session is 
    executing and the job window is in focus.
7.  Updated survival session to calculate relative median survival the first 
    time the cumulative relative estimates reaches 50%.  In prior versions, 
    if the relative percentage had reached 50% and then rose to a value above 50%
    SEER*Stat would not display a median estimate.  This is a rare instance that 
    could result in the display of a median relative statistic for a table that 
    previously was shown as can't calculate.
8.	The Survival case exclusion checkbox for excluding cases that are Alive With 
    No Survival Time is now unselected and disabled when the Presumed Alive 
    option is selected on the Parameters tab.
9.	Re-ordered the controls in the Case Listing Matrix's variable value Find 
    dialog so Field comes before Value.   Also handles a problem that could occur 
    if using find in a matrix when no cell has focus.
    
11/19/2012 - Version 8.0.1
1.  Fixed a bug in loading of table variables introduced in version
    8.0.0. The order of the variables is now preserved.
    
11/01/2012 - Version 8.0.0
1.  Changed array of session data elements to make arrays dynamic.
    Users will be warned that sessions saved with this version cannot
    be opened in older versions of SEER*Stat.
2.  Added additional multiple primary selection options to the survival
    session.  This involved adding a new drop-down list box to the bottom
    of the selection tab and removing the previous checkbox and radio 
    button from within the "Standard Selections" area of the selection tab.
3.  Added presumed alive option to survival session.  This option assumes 
    that any case not known to be dead will be considered alive on the 
    study cut-off date.
4.  Fixed loading of current databases in the data tab to exclude
    databases without valid ID numbers.  Also fixed loading of lists
    for Expected Rates and Referent rates.
5.  Upgraded the resaving of case listings to account for possible
    change in the size of the session data.
6.  Fixed a problem in the calculation of percent progress in the
    progress dialog, to prevent data overflow.
7.  Fixed the function to show Profiles on startup when only one
    profile exists. 
8.  Added ability to use delay-adjustment factors in rate/frequency
    and case listing sessions.  Requires database with factors, which
    are not currently available to research community.
In-house beta version only:
9.  Several modifications were made to the left-truncated life tables
    session.
10. Added Pohar-Perme method to survival session.  Not feature complete.
    
7/17/2012 - Version 7.1.0
1.  Fixed a problem with the MP-SIR case listing and frequency options
    that could include cases that were not part of the selected 
    database (e.g. 1975 cases for a 1992-2009 database).  This fix did
    not have any impact on the standard MP-SIR (O/E) calculations.
2.  Added a time delay when saving matrix files.  In some cases if 
    there was a latency saving the matrix, SEER*Stat would not be able 
    to save and would give an error message stating:  "updated by 
    another user".  The delay was added to avoid this issue.
3.  Added a Server Cache Refresh option to the main menu.
4.  Fixed Cum Expected Survival Method to reset to default only when
    changing to a different database.
5.  Fixed initial location of main window to avoid off-screen position
    saved from a second monitor.

4/12/2012 - Version 7.0.9
1.  Added support for Survival calculation by days.
2.  Fixed bug in Survival matrix copy with hiding zero count rows.
3.  Fixed bug to enable refresh of search statements after editing
    of invalid statements on database change.

3/5/2012 - Version 7.0.8
1.  Age Standardizing added to Survival session as an option.
2.  Survival Life Page expanding upgraded, with hiding and showing
    of zero count rows.

2/16/2012 - Version 7.0.7
1.  Fixed changing of categories for Age Variables when more than one
    age variable is available for Rate and Prevalence sessions.
2.  Remove Lost to Follow-Up from Survival session and use
    Study Cutoff in its place.
3.  Fixed MP-SIR session startup to handle database with corrupted
    cache file.

12/14/2011 - Version 7.0.6
1.  Allow invalid user variables to be fixed at session load instead
    of discarding them.
2.  Support multiple Age (for age-adjusting) variables in a single
    database.
3.  Enhanced SAS code generated by matrix export to handle imputed data.
4.  Only prompt for software autoupdate from server when installation
    file is available.
5.  Enhanced Survival session verification in client to detect when the
    number of row cells or column cells exceeds the maximum.
    
9/1/2011 - Version 7.0.5
1.  User Profile export/import now optionally includes user variables.
    Multiple profiles (and variables) can be exported at once into a
    single file.
2.  Longer variable names and grouping names are now supported.  The
    new max length is 80 chars.
3.  Added support on the data tab for a URL for database specific
    documentation.
4.  Fixed matrix export to prevent abort when preserving matrix columns.
5.  Fixed handling of hidden databases when a user profile is deleted
    from the main window menu.
6.  Shortened timeouts for various client-server interactions.
    
3/30/2011 - Version 7.0.4
1.  Fixed the default name for a new grouping in the dictionary editor.
2.  Changed handling of externally added data locations to prevent
    auto-adding of multiple server locations.
3.  On execute, verify that Prevalence session does not contain the
    Year of diagnosis field in a merged variable.
4.  Fixed handling of scrolling with mouse wheel when viewing a matrix.
    
3/15/2011 - Version 7.0.3
1.  Modified the database hiding tab in the profile dialog to show
    databases by session type.
2.  Fixed check for write access to the temporary files directory
    before downloading server cache.
3.  Added support for external adding of data locations to a profile
    by SEER*Prep or by the installation program.
    
2/11/2011 - Version 7.0.2
1.  Fixed problem that was not allowing any survival sessions to be opened.
    
2/02/2011 - Version 7.0.1
1.  New functionality was added to the survival session to support
    database-specific defaults for method for calculating cumulative
    expected survival. 
2.  Changed title/numbering of jobs and new matrices to correspond with
    title of session used to create them.
3.  Several issues related to the switch to Microsoft Visual Studio were
    resolved.
    
1/20/2011 - Version 7.0.0
1.  Changed compilers from Borland C++ builder to Microsoft Visual 
    Studio.  Previous builds were incompatible with some installations 
    of Windows.  Some users were unable to use SEER*Stat with 
    Windows 7 Ultimate.  This change should be transparent with no 
    visual differences.
2.  Profiles - The new Profile menu allows you to manage, create and use 
    profiles. A profile stores information about your preferences such 
    as data locations, directories to save files, and matrix export defaults. 
    You can also select which databases you would like to see in SEER*Stat 
    (e.g. you can hide all databases for previous submissions). You can have 
    multiple profiles and switch between them to help organize projects 
    that use different data and possibly different settings. 
3.  Ederer II was added as the default method for calculating cumulative 
    expected survival. Ederer I had been the default for calculations in 
    previous versions of SEER*Stat. A selection box for Cum Expected Method 
    was added to the survival session's statistics tab to allow you to 
    switch between Ederer II and Ederer I methods. The two options for 
    adjusting for Heterogeneity were also moved from the Output tab to 
    this new selection box.  
4.  Changes to the edit variable dialog.  When you select multiple values 
    and click Add…, you now are prompted to add as a single group or 
    individual values.
5.  The term "Limited-Use" was changed to "Research" everywhere in the 
    software.  The SEER program had made this change in all database 
    names after the previous release of SEER*Stat, so this is bringing 
    the software in-line with the database names.
6.  The MP-SIR calculations were updated in how simultaneous tumors are 
    treated when using early exit criteria. Sequence number is now 
    considered when tumors have the same event dates (date of diagnosis 
    for SIRs). The higher sequence number tumor will not be counted as 
    an event if the lower sequence number was the early exit tumor. 
7.  A problem was fixed with saving user-defined variables and case 
    listing matrix files. 
8.  Non-functional previews of future new features were included.  
    This includes the new left-truncated survival session and 
    age-adjustment for survival statistics.
      
4/1/2010 - Version 6.6.2
  1.  Removed "rate" from survival statistic references in software
      and help file.
  2.  Minor change to resolve problems with auto-update.
  3.  Minor change to make database verification more efficient when 
      using client-server mode.

2/17/2010 - Version 6.6.1 - Changed the default setting for the Select 
Only Microscopically Confirmed Standard Case Selection option in the 
Survival session back to unchecked.  The default had inadvertently been 
changed to checked in version 6.6.0.  Any new survival sessions created 
with version 6.6.0 would have the unintended default value for this option.

1/28/2010 - Version 6.6.0
  1.  A new standard exclusion checkbox was added to the survival
      session selection tab for "Alive with no Survival Time".  This
      option is checked by default in all cases.  Using the default
      setting will result in estimates that match any statistics
      generated with previous versions of SEER*Stat.
  2.  A new standard exclusion checkbox was added to the survival
      session for "Dead due to Other Causes with no Survival Time".
      This checkbox is only available when using a survival measure
      that uses cause of death rather than expected survival.  The
      default for this checkbox is database specific.  All currently
      available databases have this checkbox checked by default.
      Using the default setting will result in estimates that match
      any statistics generated with previous versions of SEER*Stat.
  3.  New checkbox added to the matrix export dialog for including
      full path of the input file in generated SAS code.
  4.  Altered the test used to determine if survival confidence
      intervals need to be flagged.  Test is explained in the
      SEER*Stat matrix footnote.
  5.  Fixed autoscroll for variable name in the dictionary edit dialog.
  6.  Fixed definition of "First Primary Only" in Selection tab for
      prevalence and MP-SIR sessions.  Was excluding prior tumors with
      sequence numbers of 60+.
  7.  Analysis options on the MP-SIR session events tab have been
      modified when using mortality rates as events.  Only single
      outcome analysis is supported, with exit at death.
  8.  Bug fix for MP-SIR table tab.  On database change, if all case
      listing variables were not valid and user cancelled, original
      list of variables was duplicated.
  9.  Bug fix for MP-SIR parameters tab.  When invalid cut points were
      provided for latency or attained calendar years, on database
      change SEER*Stat would jump to the parameters tab without warning.
 10.  Fixed a problem with multiple merged variables in a prevalence
      session.  Calculation terminated prematurely when a population
      field was included in any of the variables.

7/22/2009 - Version 6.5.2
  1.  Fixed a problem with the survival and MP-SIR session case
      listing features.  The problem would only occur if the first
      character of the first line of the title was a space.  When this
      occurred the formats for the fields were incorrect.
  2.  Changes were made to the import variable dialog to not require
      write access to the file being imported.  Wording changes were
      also made on the dialog.

4/14/2009 - Version 6.5.1 - Production release of 6.5 features.

04/7/2009 - Version 6.5.0-beta
  1. Survival session now includes confidence intervals.
  2. In the MP-SIR matrix exclusion/inclusion report, corrected a
     "double counting" of exclusions.
  3. A problem that did not allow merged variables to be included in a
     survival session case listing was corrected.
  4. Installation program now created with InstallAware rather
     than InstallShield.
  5. Minor bug fixes and interface improvements.

4/24/2008 - Version 6.4.4 - Bug fixes.
  1. In a survival matrix, if changes were made on the matrix options
     dialog, there was a memory overwrite which often caused SEER*Stat
     to shutdown and generate an error message.
  2. When opening a saved session (including retrieving one from a
     matrix) and access to the original database is no longer
     available, the database selection dialog is displayed.  Selecting
     a new database on this dialog did not reset database specific
     parameters as is done when a user changes the database on the data
     tab.  This has been changed to function like a database change on
     the data tab.

4/14/2008 - Version 6.4.3 - Production release of 6.4 features.

4/10/2008 - Version 6.4.1-beta - minor fixes

3/31/2008 - Version 6.4.0-beta
  1. Bug fix for MP-SIR.  The incorrect behavior is that all potential
     events in the rate file count as observed events, but the expected
     are calculated correctly (only for those selected), when the
     following options are chosen.
     - single outcome
     - exit on any event in the rate file
     - uncheck some of the events
     - don't include the selected event variable in the table
  2. For MP-SIR, changed the CI default from approximate to exact.
  3. For MP-SIR, changed the default exit point for single outcome
     analysis from exit on selected events to exit on any event in the
     rate file.
  4. For MP-SIR, added a checkbox for exiting at next malignant tumor
     which is on by default.
  5. SEER*Stat will now calculate an age-adjusted rate when there is a
     crude age-specific cell with non-zero cases and zero population.
  6. SEER*Stat now allows you to calculate period estimates for
     multiple user-specified years in the same session.  Previously it
     only did the latest possible year.

9/25/2007 - Version 6.3.6
 1. Exclude certain variables from case listings with the NoCaseList
    key in the database.ini.
 2. Added descriptions to user-defined variables.
 3. Only allow user information to be modified if user is logged in.
 4. Fixed page length limit for printing the survival exclusions page.
    This would hang the print request.
 5. No survival Z-test without standard life or relative rate pages.
 6. If no referent rates available, allow user to re-create rates from
    the session.
 7. Expected rates in survival are only presented when the base fields
    match.
 8. Added a prompt in the search dialog when there are selected lines
    and the user tries to paste.
 9. Merged variables are now permitted in the selection dialog.  They
    are converted, like user-defined variables, to underlying
    statements when the OK button is pressed.
10. Negative operators/prefixes are now allowed in merged variables.
11. Added a new line button on the selection dialog
12. SAS code now has lrecl= on the infile statement.

4/12/2007 - Version 6.3.5 - Production release of 6.3 features.

4/5/2007 - Version 6.3.4 - release candidate

3/19/2007 - Version 6.3.3-beta - minor fixes

2/12/2007 - Version 6.3.2-beta - minor fixes

1/23/2007 - Version 6.3.1-beta - minor fixes

1/18/2007 - Version 6.3.0-beta
 1. Allow multiple data locations instead of a primary and secondary
    data location.
 2. Changed survival matrix options so that standard errors are handled
    as a group instead of individual flags for each statistic.  This
    is the same for confidence intervals.
 3. Added special selection check boxes for "Malignant Only", "Known
    Age", "Male/Female Sex" and "Cases in Limited-Use Database" to all
    session types.
 4. The ability to specify categories for use with user-defined
    variables.
 5. Find variable dialog changed to multi-column in order to show
    matches found in the format separate from those found in the names.
 6. Allow import variable definitions from another database to the
    current database.
 7. MP-SIR rates tab: the user can see invalid rate-bases with the
    reason why they are invalid.
 8. MP-SIR rates tab: allow the use of available rate values for cohort
    values not in rates.
 9. Rate session: Tiwari method for confidence intervals.
10. Frequency or rate matrix export: added feature to preserve matrix
    columns and rename variables.
11. Survival statistic tab: missing/unknown CODs are included as dead
    broken out between specified cause and other causes.

8/31/2006 - Version 6.2.4
 1. There was an error in the prevalence session if you made a
    selection using a linked variable (a county attribute).  This was
    only a problem in the selections (not the table or cohort tabs).
    It gave an error and didn't complete; there were no incorrect
    calculations.
 2. A fix to survival for excluding cases with unknown COD.  SEER*Stat
    was excluding even when the death was after study cut-off.  Since
    SEER's COD variables use study cut-off date, most analyses on
    SEER's data would be fine.  But if the user changed the study
    cut-off date, or analyzed a user created database without recoding
    the deaths after study cut-off to alive, this would affect the
    results.
 3. A fix to survival for handling unknown/missing CODs in crude
    probability of death analyses.  There are three options: exclude,
    include as dead, include as censored.  The include as censored
    option was incorrectly including cases as dead due to other causes.
    This has been changed to include these as lost to follow-up.  We're
    planning to add a fourth option to allow the user to include them
    as dead due to other causes in a future release.
 4. Matrix export allows the creation of SAS code.
 5. Performance enhancements in the dictionary editor for the
    State-county variable.
 6. The MP-SIR session now supports databases with different variable
    for start and event dates.  Previous versions only supported date
    of cancer diagnosis for both of these dates.

4/5/2006 - Version 6.2.3 - Fix a problem which caused an MP-SIR session
to close if the first database listed didn't have referent rates.

3/29/2006 - Version 6.2.2
 1. Change to selection dialog to not accept some invalid characters.
 2. Change to not allow matrix save, print, options, etc. if while the
    matrix is open, it changes on disk.  The change could be by another
    person or by the same person having multiple copies open.
 3. Reload primary and secondary database.ini files in more situations.
 4. Fix to present database citation and database message if a
    user-supplied database is listed first.

1/19/2006 - Version 6.2.1 - Set maximum p-value of rate ratios to
1.0 and other minor fixes.

11/22/2005 - Version 6.2.0-beta
 1. More graceful handling of lost network connectivity.
 2. Go to page number in print preview.
 3. Support for large fonts.
 4. Password can optionally be remembered.
 5. Ability to display a login message obtained from the server.
 6. A Primary Data Location (PDL) is no longer required.
 7. The PDL and Secondary Data Location (SDL) can be interchanged.
 8. Faster loading of sessions when executing in local mode.
 9. Referent rates are downloaded separate and thus less often from
    the other database materials.
10. Client-server menu items are more prominent.
11. New preferences dialog to more clearly distinguish between local
    and client-server mode, and to more clearly distinguish the port
    for client-server mode.
12. Faster writing and exporting a matrix to a network location.
13. New database.ini options for disabling the case listing
    functionality in Survival and MP-SIR sessions.
14. Improved Data tab in order to more easily distinguish which
    databases have linked (SES) data.

4/14/2005 - Version 6.1.4 - More minor improvements and revised help.
Disabled profile survival method for limited-duration prevalence.

4/1/2005 - Version 6.1.3-beta - More minor interface and output
improvements.

3/24/2005 - Version 6.1.2-beta - Minor interface and output
improvements.  New help system.

3/17/2005 - Version 6.1.1-beta - Updates to median survival, standard
errors, and the Z-test for Kaplan-Meier survival.  Minor interface
fixes.

3/10/2005 - Version 6.1.0-beta
 1. Prevalence and rate sessions - statistics can be hidden based on
    population size (existing feature based on count remains).
 2. Prevalence, rate, and frequency sessions - when statistics are
    hidden based on counts, there is no suppression for 0, only
    if > 0 and less than the specified number.
 3. MP-SIR session - exact CIs (existing approximate CIs remain).
 4. Rate ratios for significance testing in the rate session.
 5. Profile survival method for limited-duration prevalence.
 6. Survival session:
    a. Kaplan-Meier survival (actuarial is still the default)
    b. New defaults:
       - 1 month intervals
       - number of intervals changed from 5 to 60 (still 5 years)
       - cumulative summary tables on
       - standard life tables off
    c. Option to include a "0th interval"
    d. Special intervals (conditional survival) can be included in
       cumulative summary tables
    e. Special intervals (conditional survival) are available for all
       cumulative statistics
    f. Matrix options dialog allows hiding statistics in cumulative
       summary tables
    g. Dimension of variables can be specified in the cumulative
       summary tables
    h. New dialog for defining intervals of cumulative summary tables
    i. Moved the display section from the output tab to the
       parameters tab
    j. Period survival for all survival session methods.
 7. Save session as an "ini" text file.
 8. Improvements to print preview that make it easier to navigate to
    the beginning, end, or specified page of a document.

10/18/2004 - Version 5.3.1
 1. Fixed error in prevalence session when selecting on age at
    prevalence.  This error was introduced in version 5.3.0.  This
    does not affect analyses with age at prevalence in the table
    definition.
 2. Fixed error in prevalence session survival calculations when the
    survival cohort variables do not include values for all records
    included in an analysis.

8/16/2004 - Version 5.3.0
 1. Ability for a single server to handle both encrypted and
    non-encrypted communications.
 2. Session printout as text.
 3. Survival now defaults to displaying percents.
 4. Merged variables now store numeric variable values in the session
    and user-defined format libraries in addition to labels.
 5. New help system.
 6. Prevalence can now be calculated by months prior instead of only
    supporting years.
 7. Blanks are now removed from MP-SIR parameters before verifying.
 8. Fixes for related variables in MP-SIR and person selection
    features of other sessions.
 9. Exclude population defining variables that can change for a
    person (e.g. county) from use in defining referent rates.  Also
    exclude related variables based on these variables.
10. Always check user-defined variables in search statements on
    database change.
11. Session printout now has title.
12. Fixed problem in survival matrix export when multiple page types
    are present.  Specifically, some export dialog options were not
    used correctly for all page types.

4/12/2004 - Version 5.2.2 - Minor fixes to client-server
communications.

4/8/2004 - Version 5.2.1-beta - Corrected a problem with status
updates in client-server mode for the prevalence session, and a
printing problem for databases without a suggested citation if
working client-server mode and the local database cache is not
available.

4/6/2004 - Version 5.2.0-beta - Encrypted communications between the
client and server.

1/15/2004 - Version 5.1.14 - Minor fixes to MP-SIR.

1/13/2004 - Version 5.1.13 - Addition of the Select Only Malignant
Behavior check box to the frequency, rate, and case listing sessions.
Minor bug fixes and additional options for ssexport under UNIX.

1/7/2004 - Version 5.1.12 - Within MP-SIR, the computations of both
"Mean Date of Exposure" and "Mean Date of Event" were updated to
correct a problem of these dates being exactly one year early.

12/19/2003 - Version 5.1.11-beta - Minor fixes.

12/17/2003 - Version 5.1.10-beta - First public release.

12/15/2003 - Version 5.1.9-beta - Updates to MP-SIR and help.

12/5/2003 - Version 5.1.8-beta - Updates to MP-SIR.

12/2/2003 - Version 5.1.7-beta - Updates to MP-SIR.

12/1/2003 - Version 5.1.6-beta - Updates to MP-SIR.

11/24/2003 - Version 5.1.5-beta - Updates to MP-SIR and help.

11/21/2003 - Version 5.1.4-beta - Updates to MP-SIR and help.

11/20/2003 - Version 5.1.3-beta - Updates to MP-SIR.

11/18/2003 - Version 5.1.2-beta - Updates to MP-SIR.

11/12/2003 - Version 5.1.1-beta - Feature complete version of MP-SIR
and new selection dialog.

9/16/2003 - Version 5.1.0-beta - Nearing a feature complete version
of MP-SIR.

9/16/2003 - Version 5.0.20 - Client now attempts a connection to PDL
seerstat.imsweb.com if seerstat.cancer.gov fails.

8/21/2003 - Version 5.0.19 - Modified selection dialog to allow work
with both continuous and discrete values of a variable.

7/21/2003 - Version 5.0.18 - Several minor updates to wording and
presentation to make things clearer and cleaner in the interface and
help system.  Added functionality post a variable specific warning
dialog.  Several other minor updates to functionality.

4/25/2003 - Version 5.0.17 - Updates to code associated with the
standard population control on the statistic tab of the rate and
prevalence sessions.

4/23/2003 - Version 5.0.16 - Updates to help.

4/15/2003 - Version 5.0.15 - Updates to help.

4/11/2003 - Version 5.0.14-beta - Updates to prevalence and
inclusion of new help.

4/4/2003 - Version 5.0.13-beta - Updates to prevalence and MP-SIR.

3/26/2003 - Version 5.0.12-beta - Inclusion of suggested citations.

3/24/2003 - Version 5.0.11-beta - Updates to MP-SIR.

3/20/2003 - Version 5.0.10-beta - Updates to prevalence and MP-SIR.

3/17/2003 - Version 5.0.9-beta - Updates to prevalence and MP-SIR.

3/12/2003 - Version 5.0.8-beta - Updates to prevalence and MP-SIR.

2/21/2003 - Version 5.0.7-beta - Wider release of the beta product.

2/19/2003 - Version 5.0.6-beta - Minor fixes.

2/14/2003 - Version 5.0.5-beta - Updates to prevalence and MP-SIR.

2/5/2003 - Version 5.0.4-beta - Updates to MP-SIR.

2/3/2003 - Version 5.0.3-beta - Updates to MP-SIR.

1/31/2003 - Version 5.0.2-beta - Updates to MP-SIR.

1/28/2003 - Version 5.0.1-beta - Updates to prevalence and MP-SIR.

1/3/2003 - Version 5.0.0-beta - Initial release with prevalence and
MP-SIR.

10/29/2002 - Version 4.2.7 - Minor fixes to the following.
 1. When merged variable base names exceeded 200 characters.
 2. Divide by zero situation in the calculation of APCs.
 3. Export dictionary when variables were reordered in the matrix.

6/6/2002 - Version 4.2.6 - Performance enhancements to the relational
model that gracefully merges socio-economic data with the cases and
populations for the generation of rates.

5/20/2002 - Version 4.2.4 - Minor fixes and the ability to disable
trends in the frequency session.  Also, the ability to independently
specify whether a database should be presented in a frequency and/or
rate session.

4/3/2002 - Version 4.2.3 - Minor fixes.

3/21/2002 - Version 4.2.2-Beta - Minor fixes and the auto-update
feature.

3/7/2002 - Version 4.2.1-Beta
 1. Relational model to gracefully merge socio-economic data with the
    cases and populations for the generation of rates.
 2. New client-server security model that uses groups to maintain
    user permissions.
 3. Checksum of user's local cache prior to client-server execution.
 4. Redesign of communication protocol for canceling a client-server
    analysis.
 5. Improvements to find variable functionality.
 6. Functionality to search for a value in a case listing matrix.
 7. Certain dialogs are now sizeable.
 8. Use of new common file dialog in Windows 2000 and XP.
 9. Ability to specify a path for storing temporary files.
10. Printing enhancements.
11. Ability to cancel a database change.
12. "Tree view" on frequency and rate table tab.
13. User generated standard populations and expected rates are
    uploaded to the server for temporary use during calculations.
14. If a database doesn't exist on session open, the user can now
    specify which database should be utilized (or attempted).

11/4/2001 - Version 4.1.4 - Set AA rates to default statistic in rate
session; minor bug fixes when switching between databases with
different age variables and standard populations; functionality to
specify default for PC end points in the database.ini.

10/16/2001 - Version 4.1.3 - Several bug fixes including a correction
to problems with exporting a case listing matrix.  Added support to
allow use of standard populations with other than 18 age groups.
SEER*Prep 1.8+ is a requirement if processing user-supplied standard
populations.

6/28/2001 - Version 4.1.2-Beta - Corrected problem with ZD sorting.

6/12/2001 - Version 4.1.1-Beta - Corrected problem of frequencies
being three times too large for population only databases.

5/24/2001 - Version 4.1.0-Beta - Split of the frequency/rate session
into two separate entities.

4/2/2001 - Version 4.0.9 - Bug fix for ZD sort not initializing cache
size properly.

3/30/2001 - Version 4.0.8 - Bug fixes.

3/29/2001 - Version 4.0.7 - Bug fixes.

3/28/2001 - Version 4.0.6 - UNIX matherr handler.

3/27/2001 - Version 4.0.5 - Bug fixes.

3/26/2001 - Version 4.0.4 - Bug fixes.

3/19/2001 - Version 4.0.3 - Bug fixes.

2/22/2001 - Version 4.0.2-beta - Generalization of variables included
in the expected rate tables to support SEER*Prep 2.0, bug fixes,
numerous minor enhancements, the ability mask out specified values of
the COD variables when they are displayed in the controls for
cause-specific survival, and the ability to filter statistics with
a decimal point in the case listing matrix.

1/8/2001 - Version 4.0.1-beta - HTML help, bug fixes, and numerous
minor enhancements.

10/10/2000 - Version 4.0.0-beta - Multiple primary selection features
in freq/rate and case listing, cause specific survival, weighted
least squares estimates for APCs, PCs with single year end-points,
case listing output from survival including the cumulative expected
rate, printing enhancements, and general interface refinements.

2/16/2001 - Version 3.0.11 - ZD bug fix for checking set size
needed for compatibility with SEER*Prep 1.5+.

9/13/2000 - Version 3.0.10 - Support for MinimumVersion= key in the
database.ini.

8/28/2000 - Version 3.0.9 - Use of ZD's operator precedence, support
for ICD-10 as a continuous variable, fixes to merged variables when
based on a user-defined, and other bug fixes.

3/27/2000 - Version 3.0.8 - Minor bug fixes over first release
candidate.

3/23/2000 - Version 3.0.7 - First release candidate of "Version 3.0".

3/3/2000 - Version 3.0.5-beta - Export enhancements, conversion of
the export dictionary to an ".ini file", and support for
user-supplied standard millions.

2/10/2000 - Version 3.0.0-beta - Initial release of the case listing
session, enhancements to merged variables, adjustments for
heterogeneity in withdrawal (Hakulinen adjustments) for relative
survival, and an option for user-defined variable definitions in the
session printout.

11/17/1999 - Version 2.1.5 - Fixes for icon problems noticeable in
earlier versions of 2.1.  Fixes for problems downloading the database
files file from the server under Windows 9x.

10/22/1999 - Version 2.1.4 - Fix to allow merged variables based on
non-indexed variables.

10/6/1999 - Version 2.1.3 - Minor bug fixes and further performance
improvements for subsetting non-indexed variables.

9/16/1999 - Version 2.1.2-beta - Improved performance for subsetting
on non-indexed variables.

9/14/1999 - Version 2.1.1-beta - Version checking between the client
and server, support for user-supplied expected rates, import/export
of user-defined variables, support for the Census tract variable, the
ability to hide PCs and APCs independently, and support for session
printouts that exceed one piece of paper.

7/16/1999 - Version 2.1 (Beta 2) - Client-server, hyperlinks in
variable descriptions, and minimize on modal status dialog.

7/7/1999 - Version 2.1 (Beta 1) - Borland C++ Builder 4 and variable
merging.  Beginnings of Hakulinen adjustments and crude survival.

3/30/1999 - Version 2.0 - Minor fixes over Beta 1.

1/22/1999 - Version 2.0 (Beta 1) - General interface refinements and
minor fixes.  Tighter integration with SEER*Prep.  Migration to
Borland C++ Builder.  Refinements to allow easier maintenance of
network installations.  Compilation of calculation module under
Solaris.  August 1998 submission of SEER, 1973-1996 diagnoses.

7/21/1998 - Version 1.1.2 - Bug fix in subset for "short" variables
with values exceeding 32k.  Needed for State/county variable.

7/9/1998 - Version 1.1.1 - Support for multiple types of summary
files.  That is, different variables in each type.

8/11/1998 - Version 1.1a - Functionality to support 1991 Canadian
standard millions.

4/3/1998 - Version 1.1 - General interface refinements and minor
fixes. August 1997 submission of SEER, 1973-1995 diagnoses.

10/15/1997 - Version 1.0 - Printing and footnote enhancements.  Help
system and general interface refinements.  August 1996 submission of
SEER, 1973-1994 diagnoses.

8/13/1997 - Version 1.0 (Beta 2) - Survival calculations and
enhancements to incidence calculations.  User-defined variables are
"memory based" by default and optionally saved to disk.  August 1996
submission of SEER, 1973-1994 diagnoses.

3/7/1997 - Beta Version 1.0 - Initial release including incidence
calculations.  February 1996 submission of SEER, 1973-1993 diagnoses.

-----------------
TECHNICAL SUPPORT
-----------------

Email: seerstat@imsweb.com

Web: www.seer.cancer.gov/seerstat