This neoplasm is not reportable.

Name

Plasma cell dyscrasia

Reportability

This neoplasm is not reportable

Alternate Names

PCD
Plasma cell dyscrasia w/IgG lambda expression

Definition

Plasma cell dyscrasia includes a diverse group of diseases that produce monoclonal immunoglobulin fragment. Reportable diseases include lymphoplasmacytic lymphoma, multiple myeloma, Waldenstrom macroglobulinemia and heavy chain disease. Non-reportable diseases include benign monoclonal gammopathy (MGUS), immunocytic amyloidosis and POEMS (polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes) syndrome.

The diagnosis of plasma cell dyscrasia is not enough to determine whether or not this is a malignancy.

Follow-up with the physician is recommended to see if further tests have been done or whether there is a clinical diagnosis of malignancy.

For plasma cell dyscrasia w/IgG lambda expression, the presence of immunoglobulins in the blood is normal, the overproduction of any one of the immunoglobulins signifies a blood disorder.
Glossary